MicroRNA-target interactions in neurodegenerative diseases
نویسندگان
چکیده
منابع مشابه
MicroRNA-target interactions in neurodegenerative diseases
MicroRNAs (miRNAs) are short, 22–25 nucleotide long transcripts that may suppress entire signaling pathways by interacting with the 3’-untranslated region (3’-UTR) of coding mRNA targets, interrupting translation and inducing degradation of these targets. The long 3’-UTRs of brain transcripts compared to other tissues predict important roles for brain miRNAs. Supporting this notion, we found th...
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MicroRNAs (miRNAs) are short, 22–25 nucleotide long transcripts that may suppress entire signaling pathways by interacting with the 3’-untranslated region (3’-UTR) of coding mRNA targets, interrupting translation and inducing degradation of these targets. The long 3’-UTRs of brain transcripts compared to other tissues predict important roles for brain miRNAs. Supporting this notion, we found th...
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ژورنال
عنوان ژورنال: SpringerPlus
سال: 2015
ISSN: 2193-1801
DOI: 10.1186/2193-1801-4-s1-l1